Anti-staphylococcal humoral immune response in persistent nasal carriers and noncarriers of Staphylococcus aureus.

@article{Verkaik2009AntistaphylococcalHI,
  title={Anti-staphylococcal humoral immune response in persistent nasal carriers and noncarriers of Staphylococcus aureus.},
  author={Nelianne J. Verkaik and Corn{\'e} P. de Vogel and H{\'e}l{\`e}ne A.M. Boelens and Dorothee Grumann and Theo Hoogenboezem and Cornelis Vink and Herbert Hooijkaas and T. J. Foster and Henri A. Verbrugh and Alex van Belkum and Willem J. B. van Wamel},
  journal={The Journal of infectious diseases},
  year={2009},
  volume={199 5},
  pages={625-32}
}
BACKGROUND Persistent carriers have a higher risk of Staphylococcus aureus infections than noncarriers but a lower risk of bacteremia-related death. Here, the role played by anti-staphylococcal antibodies was studied. METHODS Serum samples from 15 persistent carriers and 19 noncarriers were analyzed for immunoglobulin (Ig) G, IgA, and IgM binding to 19 S. aureus antigens, by means of Luminex technology. Nasal secretions and serum samples obtained after 6 months were also analyzed. RESULTS… CONTINUE READING