Anti-rheumatic drugs and joint damage in rheumatoid arthritis.

@article{Scott1985AntirheumaticDA,
  title={Anti-rheumatic drugs and joint damage in rheumatoid arthritis.},
  author={David Lloyd Scott and Peter T. Dawes and Patrick W. Fowler and K. A. Grindulis and Michael F Shadforth and Paul A. Bacon},
  journal={The Quarterly journal of medicine},
  year={1985},
  volume={54 213},
  pages={
          49-59
        }
}
The effect of second-line anti-rheumatic drugs such as gold on the course and progression of joint damage has been the subject of considerable controversy. We have evaluated the effects of second-line anti-rheumatic drugs in three studies of 46-84 patients with rheumatoid arthritis given a second-line drug continuously for 12 months. Using two different methods of radiographic assessment we found that there was significant progression over the 12-month period when the mean changes in the groups… CONTINUE READING
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