Anti-prostate cancer activity of a beta-carboline alkaloid enriched extract from Rauwolfia vomitoria.

  title={Anti-prostate cancer activity of a beta-carboline alkaloid enriched extract from Rauwolfia vomitoria.},
  author={Debra Bemis and Jillian L. Capodice and Prakash Gorroochurn and Aaron E. Katz and Ralph Buttyan},
  journal={International journal of oncology},
  volume={29 5},
The tropical shrub, Rauwolfia vomitoria, is a medicinal plant used traditionally to treat a variety of ailments. A bioactive beta-carboline alkaloid, alstonine, present in this extract was previously shown to have anti-cancer activity against cancer cell lines. This study considers the potential anti-prostate cancer activity of this extract in vitro and in vivo. Rauwolfia vomitoria extract standardized for beta-carboline alkaloids was tested for ability to influence the growth and survival of… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 24 references

A role for cyclin A 1 in mediating the autocrine expression of vascular endothelial growth factor in prostate cancer

M Pagano, R Pepperkok, F Verde, W Ansorge, G Draetta
Oncogene • 2005

Management of advanced prostate cancer after first-line chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2005

PDRHealth . com . Rauwolfia

M Beljanski, MS Beljanski
BJU Int • 2005

The cyclin A 1 - CDK 2 complex regulates DNA double - strand break repair

LJ Ko, SY Shieh, +5 authors ZQ Pan
Mol Cell Biol • 2004

Classific - ation of anticancer drugs - a new system based on therapeutic targets

MB Kastan, J Bartek
Cancer Treat Rev • 2003

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