Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells.

  title={Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells.},
  author={L C Chiang and Lean Teik Ng and I-Cheng Lin and Po-Lin Kuo and Chun-Ching Lin},
  journal={Cancer letters},
  volume={237 2},
Apigenin, a common dietary flavonoid abundantly present in fruits and vegetables, is believed to possess preventive and therapeutic potential against cancers. In this study, the anti-hepatoma property of apigenin was evaluated on three different human hapatoma cells, namely Hep G2, Hep 3B, and PLC/PRF/5 cells. Results showed that apigenin exhibited a significant growth inhibition against the three selected hepatoma cell lines but not the normal murine liver BNL CL.2 cells. Interestingly, it was… CONTINUE READING


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