Anti-programmed cell death-1 antibody as a new serological marker for type 1 autoimmune hepatitis.

@article{Matsumoto2014AntiprogrammedCD,
  title={Anti-programmed cell death-1 antibody as a new serological marker for type 1 autoimmune hepatitis.},
  author={Kazuyuki Matsumoto and Yasuhiro Miyake and Hiroshi Matsushita and Atsuyuki Ohnishi and Fusao Ikeda and Hidenori Shiraha and Akinobu Takaki and Kazuhiro Nouso and Kazuhide Yamamoto},
  journal={Journal of gastroenterology and hepatology},
  year={2014},
  volume={29 1},
  pages={110-5}
}
BACKGROUND AND AIM Recently, the association of the dysfunction of programmed cell death (PD)-1 expressed on activated lymphocytes with the pathogenesis of autoimmune hepatitis (AIH) has been speculated. This study aimed to investigate the association of serum anti-PD-1 antibodies with clinical characteristics of type 1 AIH. METHODS Serum samples before the initiation of prednisolone treatment were obtained from 52 type 1 AIH patients, 24 patients with drug-induced liver injury (DILI), 30… CONTINUE READING