Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula.

@article{Santos2015AntiparasiticGA,
  title={Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula.},
  author={Mario F.C. Santos and Philip M Harper and David E. Williams and Juliana Tonini Mesquita and {\'E}rika Gracielle Pinto and Thais Alves da Costa-Silva and Eduardo Hajdu and Antonio Gilberto Ferreira and Raquel Alves Dos Santos and Patrick J. Murphy and Raymond J. Andersen and Andr{\'e} Gustavo Tempone and Roberto G. S. Berlinck},
  journal={Journal of natural products},
  year={2015},
  volume={78 5},
  pages={
          1101-12
        }
}
HPLC-UV-ELSD-MS-guided fractionation of the anti-parasitic extract obtained from the marine sponge Monanchora arbuscula, collected off the southeastern coast of Brazil, led to the isolation of a series of guanidine and pyrimidine alkaloids. The pyrimidines monalidine A (1) and arbusculidine A (7), as well as the guanidine alkaloids batzellamide A (8) and hemibatzelladines 9-11, represent new minor constituents that were identified by analysis of spectroscopic data. The total synthesis of… 
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