Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin.
@article{Maoka2013AntioxidativeAA, title={Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin.}, author={Takashi Maoka and Hiroyuki Yasui and Aya Ohmori and Harukuni Tokuda and Nobutaka Suzuki and Ayako Osawa and Kazutoshi Shindo and Takashi Ishibashi}, journal={Journal of oleo science}, year={2013}, volume={62 3}, pages={ 181-6 } }
Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin, which are biosynthetic intermediates from β-carotene to astaxanthin, were investigated. Both adonirubin and adonixanthin showed almost the same activities for inhibition of lipid peroxidation and quenching of singlet oxygen as those of astaxanthin. Furthermore, adonirubin and adonixanthin exhibited an inhibitory effect on Epstein-Barr virus early antigen activation in Raji cells and…
29 Citations
Anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol and lupeol isolated from Diospyros lotus L.
- Chemistry, MedicineNatural product research
- 2016
Both the compounds exhibited a marked anti-tumour-promoting and potent inhibitory effect on thermal-induced protein denaturation on heat-inducedprotein denaturation.
Protective effects of the astaxanthin derivative, adonixanthin, on brain hemorrhagic injury
- BiologyBrain Research
- 2018
Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma
- BiologyMarine drugs
- 2020
Astaxanthin and adonixanthin showed an ability to suppress cell proliferation and migration in three types of glioblastoma cells and were confirmed to transfer to the brain in a murine model.
Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration.
- Biology, Environmental ScienceJournal of pharmacological sciences
- 2017
On a Beam of Light: Photoprotective Activities of the Marine Carotenoids Astaxanthin and Fucoxanthin in Suppression of Inflammation and Cancer
- BiologyMarine drugs
- 2020
Astaxanthin and fucoxanthin are peculiar marine carotenoids characterized by outstanding antioxidant properties and ASX showed exceptional efficacy in counteracting all categories of photodamages, in vitro and in vivo, thanks to both antioxidant potential and activation of alternative pathways.
A sub-chronic toxicity evaluation of a natural astaxanthin-rich carotenoid extract of Paracoccus carotinifaciens in rats
- BiologyToxicology reports
- 2014
Central Nervous System Migration of Astaxanthin and Adonixanthin Following Their Oral Administration in Cynomolgus Monkeys.
- BiologyJournal of nutritional science and vitaminology
- 2020
Findings indicate that astaxanthin and adonixanthin can enter the central nervous system of primates following their oral administration, and provides important evidence for the activity of astax anthin andadonxanthin on thecentral nervous system.
Enriched Astaxanthin Extract from Haematococcus pluvialis Augments Growth Factor Secretions to Increase Cell Proliferation and Induces MMP1 Degradation to Enhance Collagen Production in Human Dermal Fibroblasts
- BiologyInternational journal of molecular sciences
- 2016
It was noticeable that EAE had a positive impact on cell proliferation and vascular endothelial growth factor (VEGF) than doxycycline, indicating that it was a better alternative treatment for collagen production.
HIDROCARBUROS AROMÁTICOS POLICÍCLICOS (HAPs) (II): MEDIDAS DE PREVENCIÓN Y CONTROL POLYCYCLIC AROMATIC HYDROCARBONS (PAHs) (II): MEASURES OF PREVENTION AND CONTROL
- Medicine
- 2016
Measures of prevention and control against polycyclic aromatic hydrocarbons (PAHs) focus on an official food control, a code of best practice to reduce PAHs levels by controlling industry and in the…
Nutraceutical and Pharmaceutical Applications of Carotenoids
- Chemistry
- 2020
Carotenoids, the most common fat-soluble plant pigments in nature, play important roles in scavenging peroxyl radicals and singlet oxygen in human. Dietary carotenoids are considered to be beneficial…
References
SHOWING 1-10 OF 25 REFERENCES
Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L.
- Chemistry, BiologyCancer letters
- 2001
Inhibitory effect of natural carotenoids on Epstein-Barr virus activation activity of a tumor promoter in Raji cells. A screening study for anti-tumor promoters.
- ChemistryBiological & pharmaceutical bulletin
- 1995
As a screening study for anti-tumor promoters, 51 carotenoids with diverse structures were examined for their inhibitory effects on the Epstein-Barr virus activation activity of…
Antioxidant activity of β-carotene-related carotenoids in solution
- ChemistryLipids
- 2006
The effect of the antioxidant activity of β-carotene and related carotenoids on the free radical-oxidation of methyl linoleate in solution was examined by measuring the production of methyl linoleate…
Astaxanthin, a carotenoid with potential in human health and nutrition
- Medicine, Biology
- 2006
In this review, the recent scientific literature is covered on the most significant activities of compound 1, including its antioxidative and anti-inflammatory properties, its effects on cancer, diabetes, the immune system, and ocular health, and other related aspects.
Astaxanthin, a carotenoid with potential in human health and nutrition.
- Medicine, BiologyJournal of natural products
- 2006
In this review, the recent scientific literature is covered on the most significant activities of compound 1, including its antioxidative and anti-inflammatory properties, its effects on cancer, diabetes, the immune system, and ocular health, and other related aspects.
Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin.
- MedicineCancer research
- 1995
The results indicate that AX and CX are possible chemopreventers for oral carcinogenesis, and such effects may be partly due to suppression of cell proliferation.
Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase.
- Biology, MedicineCarcinogenesis
- 1995
The results indicate that AX and CX are possible chemopreventers for carcinogenesis of colon in addition to urinary bladder and oral cavity and such effects may be partly due to suppression of cell proliferation.
Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin.
- Medicine, BiologyCarcinogenesis
- 1994
AX is a possible chemopreventive agent for bladder carcinogenesis and such an effect of AX may be partly due to suppression of cell proliferation, as indicated by results of mice treated with AX or CX.
Suppression of Azoxymethane‐induced Rat Colon Aberrant Crypt Foci by Dietary Protocatechuic Acid
- Biology, MedicineJapanese journal of cancer research : Gann
- 1994
Evidence is provided that PCA could be a chemopreventive agent against rat colon carcinogenesis and the frequency of ACF/colon was significantly decreased, and the mean AgNORs count in rats fed PCA was significantly smaller than that of rats treated with AOM alone.
Antioxidative Activity of Capsorubin and Related Compounds from Paprika (Capsicum annuum)
- Chemistry, Biology
- 2001
The antioxidative activities of capsorubin and related compounds isolated from paprika inhibited the oxidation of methyl linolate in solution initiated by 2,2'-azobis(2,4-dimethyl vareronitrile) (AMVN).