Corpus ID: 55156145

Anti obesity mechanism of Curcuma longa L.: An Over view

@article{Yadav2016AntiOM,
  title={Anti obesity mechanism of Curcuma longa L.: An Over view},
  author={Kapil Yadav and Anand Kumar Chaudhary},
  journal={Indian Journal of Natural Products and Resources},
  year={2016},
  volume={7},
  pages={99-106}
}
Chronic low grade inflammation is one important reason for the development of obesity and the inflammation is initiated by excess nutrient from metabolic cell and is characterized by increasing TNFα, interlukins, cytokinines, etc. Besides this, genetic, social, behavioural and environmental factors alone or interaction with each other influences diet, physical activity by affecting complex hypothalamic neuro-circuitry. These increase leptin level, inflammatory mediators and reactive oxygen… Expand

Tables from this paper

Antidiabetic Potential of Medicinal Plants and Their Active Components
TLDR
Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. Expand
Antiobesity and Antioxidant Potentials of Selected Palestinian Medicinal Plants
TLDR
Natural resources that possess strong antioxidant and pancreatic lipase inhibitory activities with potential applications in the treatment and prevention of obesity and overweight are suggested. Expand
Bioactives in spices, and spice oleoresins: Phytochemicals and their beneficial effects in food preservation and health promotion
TLDR
A summary of the most relevant and recent findings on phytochemical composition and antioxidant properties of spices has been compiled and discussed. Expand
Aktivitas Antibakteri Ekstrak Aseton Rimpang Kunyit (Curcuma domestica) terhadap Bakteri Staphylococcus aureus dan Escherichia coli
ABSTRAK Kunyit (Curcuma domestica) merupakan suatu tumbuhan yang telah digunakan sejak lama sebagai obat tradisional. Rimpang kunyit digunakan untuk mengatasi berbagai masalah kesehatan sepertiExpand

References

SHOWING 1-10 OF 100 REFERENCES
Curcumin improves hypoxia induced dysfunctions in 3T3-L1 adipocytes by protecting mitochondria and down regulating inflammation.
TLDR
Investigation of how hypoxia affect the physiological functions of 3T3-L1 adipocytes emphasizing on oxidative stress, inflammation, and mitochondrial functions and the protective role of curcumin revealed that it substantially protected adipocytes from toxic effects ofHypoxia in a dose dependent manner by protecting mitochondria and down regulating inflammation. Expand
Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling.
TLDR
It is demonstrated that curcumin abrogates the stimulatory effect of leptin on HSC activation in vitro by reducing the phosphorylation level of Ob-R, stimulating peroxisome proliferator-activated receptor-gamma activity, and attenuating oxidative stress, leading to the suppression of ob-R gene expression and interruption of leptin signaling. Expand
Inflammation and insulin resistance.
TLDR
The evolving concept of insulin resistance and T2D as having immunological components and an improving picture of how inflammation modulates metabolism provide new opportunities for using antiinflammatory strategies to correct the metabolic consequences of excess adiposity. Expand
Pharmacology of Curcuma longa.
TLDR
It appears that when given orally, curcumin is far less active than after i.p. administration, and systemic effects seem to be questionable after oral application except that they occur at very low concentrations ofCurcumin, which does not exclude a local action in the gastrointestinal tract. Expand
Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come.
TLDR
Recent research has revealed many functions of adipocytokines extending far beyond metabolism, such as immunity, cancer and bone formation, which may be of particular importance for the clinician. Expand
Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols.
TLDR
The experimental data indicated that the molecular mechanisms of fatty acid synthase gene suppression by tea polyphenols (EGCG, theaflavins) may invite down-regulation of EGFR/PI3K/Akt/Sp-1 signal transduction pathways. Expand
Regulation of adiponectin production by insulin: interactions with tumor necrosis factor-α and interleukin-6.
TLDR
In conclusion, these studies show that insulin upregulates adiponectin expression and release, and that TNF-α opposes the stimulatory effects of insulin. Expand
Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats
TLDR
It is suggested that FCE50 can be a candidate for the prevention of obesity via suppressing adipogenesis and promoting lipolysis and up-regulating the expression of lipases such as adipose triglyceride lipase, hormone-sensitivelipase, adiponectin, and AMP-activated protein kinase. Expand
Curcumin as "Curecumin": from kitchen to clinic.
TLDR
Curcumin, a spice once relegated to the kitchen shelf, has moved into the clinic and may prove to be "Curecumin", a therapeutic agent in wound healing, diabetes, Alzheimer disease, Parkinson disease, cardiovascular disease, pulmonary disease, and arthritis. Expand
Curcumin Attenuates Diet‐Induced Hepatic Steatosis by Activating AMP‐Activated Protein Kinase
TLDR
Findings indicate that curcumin attenuates HFD‐induced hepatic steatosis by regulating hepatic lipid metabolism via AMPK activation, suggesting its use as a therapeutic for hepatic Steatosis. Expand
...
1
2
3
4
5
...