Anti-obesity drugs and neural circuits of feeding.

  title={Anti-obesity drugs and neural circuits of feeding.},
  author={Roger A H Adan and Louk J. M. J. Vanderschuren and Susanne E la Fleur},
  journal={Trends in pharmacological sciences},
  volume={29 4},
Most of the drugs that have entered the market for treating obesity were originally developed to treat psychiatric diseases. During the past decade, understanding of the neural circuits that underlie food intake has increased considerably. Different aspects of ingestive behavior such as meal termination, meal initiation and overconsumption of highly rewarding and palatable foods are modulated by different neuroanatomical structures. Integration of the action of many signaling molecules (e.g… CONTINUE READING


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