Anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta 3-adrenoceptor agonist, in yellow KK mice.

Abstract

The anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta 3-adrenoceptor agonist (beta 1: beta 2: beta 3 = 0:1:100,000), were evaluated in obese diabetic yellow KK mice and C57Bl control mice. The study compound was fed through a gastric tube at a rate of 0.1 mg/kg/day for 2 weeks. The following parameters were compared in the treated… (More)

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@article{Yoshida1994AntiobesityAA, title={Anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta 3-adrenoceptor agonist, in yellow KK mice.}, author={T. Yoshida and Naoki Sakane and Yoshiyuki Wakabayashi and Takashi Umekawa and M. Kondo}, journal={Life sciences}, year={1994}, volume={54 7}, pages={491-8} }