Anti-mucus polyclonal antibody production, purification and linkage to the surface of albumin microspheres.

Abstract

This aim of this study was to develop a microparticulate based oral drug delivery system, which could prolong gut transit time by binding via specific interactions to the gut mucus layer. Porcine gastric mucus was semi-purified and used as an antigen to raise a polyclonal antiserum in rabbits. The immunoglobulin fraction of this serum was isolated, purified… (More)

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Cite this paper

@article{Macadam2000AntimucusPA, title={Anti-mucus polyclonal antibody production, purification and linkage to the surface of albumin microspheres.}, author={Angela Macadam and Zaki Shafi and Christopher Marriott and G P Martin and Shelly L James}, journal={International journal of pharmaceutics}, year={2000}, volume={195 1-2}, pages={147-58} }