Anti-microbial activities of mannose-binding lectin.

@article{Jack2003AntimicrobialAO,
  title={Anti-microbial activities of mannose-binding lectin.},
  author={Dominic L. Jack and Malcolm W. Turner},
  journal={Biochemical Society transactions},
  year={2003},
  volume={31 Pt 4},
  pages={
          753-7
        }
}
Mannose-binding lectin (MBL; also known as mannan-binding lectin) is involved in first-line defence by binding to bacteria, viruses, protozoa and helminths through a pattern-recognition mode of detection and then initiating a range of host responses. Currently, we have been unable to extrapolate from what we know of the biochemistry of MBL binding to predict accurately the interaction of MBL with individual micro-organisms; even subtle surface alterations have been shown to have an extensive… CONTINUE READING

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