Anti-malarial drugs: possible mechanisms of action in autoimmune disease and prospects for drug development

@article{Fox1996AntimalarialDP,
  title={Anti-malarial drugs: possible mechanisms of action in autoimmune disease and prospects for drug development},
  author={R. Fox},
  journal={Lupus},
  year={1996},
  volume={5},
  pages={10 - 4}
}
Correspondence: R Fox, Division of Rheumatology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, MS113, La Jolla, CA 92037, USA A wide variety of mechanisms of anti-rheumatic action have been proposed for antimalarial agents. The molecular actions of chloroquine have been most thoroughly studied in vitro and in vivo, but it is likely that hydroxychloroquine works by a similar mechanism. Both agents are weak diprotic bases that can pass through the lipid cell membrane and… Expand

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