Anti-invasive activity of alkaloids and polyphenolics in vitro.

@article{Parmar1997AntiinvasiveAO,
  title={Anti-invasive activity of alkaloids and polyphenolics in vitro.},
  author={V. S. Parmar and M. Bracke and J. Philippe and J. Wengel and S. Jain and C. Olsen and K. S. Bisht and N. Sharma and A. Courtens and S. Sharma and K. Vennekens and V. van Marck and S. Singh and N. Kumar and A. Kumar and S. Malhotra and R. Kumar and V. Rajwanshi and R. Jain and M. Mareel},
  journal={Bioorganic \& medicinal chemistry},
  year={1997},
  volume={5 8},
  pages={
          1609-19
        }
}
Invasiveness, the ability of certain tumour cells to migrate beyond their natural tissue boundaries, often leads to metastasis, and usually determines the fatal outcome of cancer. The need for anti-invasive agents has led us to search for possibly active compounds among alkaloids and polyphenolics. One hundred compounds were screened in an assay based on the confrontation of invasive human MCF-7/6 mammary carcinoma cells with fragments of normal embryonic chick heart in vitro. Anti-invasive… Expand
Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.
  • C. Miranda, J. F. Stevens, +6 authors D. Buhler
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1999
Chick heart invasion assay.
Chick heart invasion assay.
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