Anti-interleukin-17 antibodies attenuate airway inflammation in tobacco-smoke-exposed mice.

@article{Shen2011Antiinterleukin17AA,
  title={Anti-interleukin-17 antibodies attenuate airway inflammation in tobacco-smoke-exposed mice.},
  author={Ning Shen and Jing Wang and Mingwu Zhao and Fei Pei and Bei He},
  journal={Inhalation toxicology},
  year={2011},
  volume={23 4},
  pages={212-8}
}
CONTEXT Our previous study showed that the interleukin-17 (IL-17) concentration in lung tissue and in bronchoalveolar lavage fluid (BALF) of rats with tobacco-smoke-induced chronic obstructive pulmonary disease (COPD) was higher than that of control group. However, whether IL-17 inhibitor could decrease the effect of tobacco smoking is not known yet. OBJECTIVES To investigate the significance of IL-17 antibodies (Ab) in tobacco-smoke-exposed (TSE) mice. MATERIALS AND METHODS Male C57/BL6… CONTINUE READING