Anti-inflammatory therapies in cancer cachexia.

@article{Argils2011AntiinflammatoryTI,
  title={Anti-inflammatory therapies in cancer cachexia.},
  author={Josep Mar{\'i}a Adell Argil{\'e}s and Silvia Josefina Busquets and Francisco Javier L{\'o}pez-Soriano},
  journal={European journal of pharmacology},
  year={2011},
  volume={668 Suppl 1},
  pages={
          S81-6
        }
}
Disease progression in cancer is dependent on the complex interaction between the tumor and the host inflammatory response. Indeed, both the tumor and the patient produce cytokines that act on multiple target sites such as bone marrow, myocytes, hepatocytes, adipocytes, endothelial cells and neurons, where they produce a complex cascade of biological responses leading to the wasting associated with cachexia. The cytokines that have been involved in this cachectic response are TNF-alpha, IL-1… CONTINUE READING
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