Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata.

  title={Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata.},
  author={Min Yan and Ying Zhu and Hong-jun Zhang and Wei-Hua Jiao and Bing-Nan Han and Zhao-xi Liu and Feng Qiu and Wansheng Chen and Hou-Wen Lin},
  journal={Bioorganic & medicinal chemistry},
  volume={21 11},
Bioassay-guided fractionation of a n-BuOH-soluble extract of the leaves of Rosa laevigata led to the isolation of three new 19-oxo-18,19-seco-ur-sane-type triterpenoids, laevigins A-C (1-3), a new oleanane-type triterpenoid saponin, laevigin D (4), a new geranylmethylbenzoate, 5-[(2″E,6″S)-6″,7″-dihydroxy-3″,7″-dimethyl-2″-octen-1″-yl]-2-(β-D-glucopyranosyloxy)-methyl benzoate (5), together with 9 known compounds (6-14). Their structures were elucidated by spectroscopic and chemical methods… CONTINUE READING

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