Anti-inflammatory plant flavonoids and cellular action mechanisms.

@article{Kim2004AntiinflammatoryPF,
  title={Anti-inflammatory plant flavonoids and cellular action mechanisms.},
  author={Hyun Pyo Kim and Kun Ho Son and Hyeun Wook Chang and Sam Sik Kang},
  journal={Journal of pharmacological sciences},
  year={2004},
  volume={96 3},
  pages={
          229-45
        }
}
Plant flavonoids show anti-inflammatory activity in vitro and in vivo. Although not fully understood, several action mechanisms are proposed to explain in vivo anti-inflammatory action. One of the important mechanisms is an inhibition of eicosanoid generating enzymes including phospholipase A2, cyclooxygenases, and lipoxygenases, thereby reducing the concentrations of prostanoids and leukotrienes. Recent studies have also shown that certain flavonoids, especially flavone derivatives, express… CONTINUE READING

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