Anti-inflammatory effects of four potential anti-endotoxaemic drugs assessed in vitro using equine whole blood assays.

@article{Bauquier2015AntiinflammatoryEO,
  title={Anti-inflammatory effects of four potential anti-endotoxaemic drugs assessed in vitro using equine whole blood assays.},
  author={J R Bauquier and Edgar G Tudor and S R Bailey},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2015},
  volume={38 3},
  pages={290-6}
}
Despite the severity and common occurrence of equine endotoxaemia, the available anti-endotoxic treatments do not effectively target key inflammatory mechanisms such as leucocyte activation and cytokine production. In this study, four compounds with potential anti-endotoxic effects, namely rolipram, azithromycin, ethyl pyruvate and metformin, were investigated in vitro using equine whole blood stimulated with bacterial lipopolysaccharide. TNF-α and IL-1β production were measured in plasma… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
1 Citations
38 References
Similar Papers

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 38 references

The effect of oral metformin on insulin sensitivity

  • G. K. Noble
  • 2012

Similar Papers

Loading similar papers…