Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis.

  title={Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis.},
  author={Kazuhiro Ohgami and Iliyana Bozhidarova Ilieva and Kenji Shiratori and Yoshikazu Koyama and Xue-hai Jin and Kazuhiko Yoshida and Satoru Kase and Nobuyoshi Kitaichi and Yukari Suzuki and Tsuneo Tanaka and Shigeaki Ohno},
  journal={Investigative ophthalmology & visual science},
  volume={46 1},
PURPOSE Aronia crude extract (ACE) with high levels of polyphenol compounds has been reported to have antioxidative effects in vitro and in vivo. In this study, attention was focused on the antioxidant effect of ACE. The purpose of the present study was to investigate the effect of ACE on endotoxin-induced uveitis (EIU) in rats. In addition, the endotoxin-induced expression of the inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins was investigated in a mouse macrophage… CONTINUE READING
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