Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.

@article{Hoareau2009AntiinflammatoryEO,
  title={Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.},
  author={Laurence Hoareau and Marion Buyse and Franck Festy and Palaniyandi Ravanan and Michel Gonthier and I Catarina Matias and Stefania Rehnelt Jennifer Petrosino and Frank Tallet and Christian Lefebvre D'hellencourt and Maya M. Cesari and Vincenzo Di Marzo and R{\'e}gis Roche},
  journal={Obesity},
  year={2009},
  volume={17 3},
  pages={
          431-8
        }
}
Obesity leads to the appearance of an inflammatory process, which can be initiated even with a moderate weight gain. Palmitoylethanolamide (PEA) is an endogenous lipid, secreted by human adipocytes, that possesses numerous anti-inflammatory properties. The main purpose of this study was to investigate the anti-inflammatory effect of PEA on human adipocytes, as well as in a murine model. The production of tumor necrosis factor-alpha (TNF-alpha) by lipopolysaccharide (LPS)-treated human… CONTINUE READING
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