Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.

@article{Sandoval2002AntiinflammatoryAA,
  title={Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.},
  author={Manuel Sandoval and Nataly N. Okuhama and X J Zhang and L. A. Condezo and Juan Lao and Fausto M Angeles and Rabi Ann Musah and Paul J. Bobrowski and M J Miller},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2002},
  volume={9 4},
  pages={
          325-37
        }
}
Cat's claw is an herbal medicine from the Amazon that is used widely to treat inflammatory disorders. The purpose of this study was to characterize the antioxidative and antiinflammatory properties of cat's claw, Uncaria tomentosa (UT) and Uncaria guianensis (UG). Alkaloids and flavanols were determined using reversed-phase HPLC; scavenging of 1,1-diphenyl-2-picrilhydrazyl (DPPH), hydroxyl radicals, and lipid peroxidation by spectrophotometry; and TNFalpha production by ELISA. Anti-inflammatory… 

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