Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum.

Abstract

Bioassay-directed fractionation of an extract of the New Zealand ascidian Aplidium scabellum has afforded the anti-inflammatory secondary metabolite 2-geranyl-6-methoxy-1,4-hydroquinone-4-sulfate (1) and a family of pseudodimeric meroterpenoids scabellones A (2)-D (5). The benzo[c]chromene-7,10-dione scaffold contained within scabellones A-D is particularly… (More)
DOI: 10.1021/jo201654h

Topics

Cite this paper

@article{Chan2011AntiinflammatoryAA, title={Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum.}, author={Susanna T S Chan and A. Norrie Pearce and Ana Helena Janu{\'a}rio and Michael J. Page and M Kaiser and Rene J. McLaughlin and Jacquie L. Harper and Victoria L Webb and David Barker and Brent R Copp}, journal={The Journal of organic chemistry}, year={2011}, volume={76 21}, pages={9151-6} }