Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea.

  title={Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea.},
  author={Giselle Fazzioni Passos and Elizabeth Soares Fernandes and Fernanda M da Cunha and Juliano Ferreira and Luiz Francisco Pianowski and Maria Martha Campos and Jo{\~a}o B. Calixto},
  journal={Journal of ethnopharmacology},
  volume={110 2},

Evaluation of Anti-Inflammatory Activity of Citrus latifolia Tanaka Essential Oil and Limonene in Experimental Mouse Models

It is shown that LIM isolated from CLEO had potential anti-inflammatory effects, likely by inhibiting proinflammatory mediators present in inflammatory exudate and leukocyte chemotaxis.

Evaluation of analgesic and anti-inflammatory activities of Hydrocotyle umbellata L., Araliaceae (acariçoba) in mice.

Results showed that EEA of H. umbellata L. presents analgesic and anti-inflammatory activities, and that a blockade of activity or reduction in the release of different mediators, such as histamine and serotonin, could be involved in these pharmacologic effects.

Anti-inflammatory and anti-hypersensitive effects of the chalcone isocordoin and its semisynthetic derivatives in mice

The results of this investigation indicate that both monoalkylation of the C-4′ phenolic hydroxyl group and reduction of the double bond in the α,β-unsaturated system of the chalcone skeleton favor activity.

Chemical Constituents, Anti-nociceptive and Anti-inflammatory Activities of Essential Oil of Phyllanthus muellerianus

The essential oils of P. muellerianus depressed the nociceptors and most likely acted as centrally mediated opioid analgesics while the anti-inflammatory mechanisms of the oil might be related to the decrease in the level of iNOS, and cyclo-oxygenase-2 in the edema paw via the suppression of pro-inflammatory cytokines.

Anti-Inflammatory and Antioxidant Effects of the Indole-Derived N-Salicyloyltryptamine on Peritonitis and Joint Disability Induced by Carrageenan in Rodents

NST presented anti-inflammatory and antioxidant effects in experimental models of carrageenan-induced peritonitis and joint disability in mice and rats, respectively, which may be related to the modulation of neutrophils migration as well as the involvement of antioxidant mechanisms.



Anti-allergic effects and oedema inhibition caused by the extract of Drymis winteri

The results confirm and extend the previous studies, and demonstrate the clear oral anti-inflammatory and anti-allergic properties of the active principle(s) present in the barks of D. winteri, thus confirming its reported medicinal use in folk medicine for the management of airway diseases.

Analysis of the inflammatory response in the rat paw caused by the venom of Apis melifera bee

The results indicate that the BV from Apis melifera causes a marked dose-and time-dependent oedema formation in the rat paw, an effect that is accompanied by intense leukocyte migration.

Anti-inflammatory activity and sub-acute toxicity of artemetin.

The 5-hydroxy-3,6,7,3',4'-pentamethoxyflavone (artemetin) from Cordia verbenacea DC (Boraginaceae) showed marked anti-inflammatory activity using various experimental models in rats and sub-acute toxicological experiments indicated a very low toxicity.

Anti-inflammatory activity of macrolide antibiotics.

The present study shows that macrolide antibiotics have anti-inflammatory activity, which likely depends on their ability to prevent the production of proinflammatory mediators and cytokines, and suggests that these agents, particularly roxithromycin, can exert therapeutic effects independently of their antibacterial activity.

Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation

Together these results provide consistent evidence indicating that the selective COX-2 inhibitors CLX and RFX, in contrast to DEX, INDO or SC-560, despite reducing greatly the Cg-induced pleural exudation, PGE2 content and paw oedema have only partial acute anti-inflammatory properties in two different rat acute models of inflammation.

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

It is indicated that PGE2 plays a major role in tissue edema, hyperalgesia, and IL-6 production at sites of inflammation, and it is suggested that selective pharmacologic modulation of P GE2 synthesis or activity may provide a useful means of mitigating the symptoms of inflammatory disease.

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

  • K. SeibertY. Zhang P. Isakson
  • Medicine, Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1994
In an animal model of acute inflammation, a selective inhibitor of COX-2 inhibited edema at the inflammatory site and was analgesic but had no effect on PG production in the stomach and did not cause gastric toxicity.