Corpus ID: 87352756

Anti-inflammatory and Cytotoxic Activities of Mango (Mangifera indica L. var Keitt) Polyphenols in Cancer and Non-cancer Breast Fibroblasts in Vitro

  title={Anti-inflammatory and Cytotoxic Activities of Mango (Mangifera indica L. var Keitt) Polyphenols in Cancer and Non-cancer Breast Fibroblasts in Vitro},
  author={Shirley Arbizu Berrocal},
Improved Extraction of Acylated Anthocyanins from Purple Sweet Potato (Ipomoea Batata) for Enhanced Anti-inflammatory Activity and Their Metabolite Production During Porcine Fecal Digestion
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Polyphenolics from Mango (Mangifera Indica L.) Suppress Breast Cancer Ductal Carcinoma In Situ Proliferation Both In Vitro And In Vivo: Potential Role of the IGFR-1-AKT-AMPK-mTOR-Signaling Axis
The aim of this chapter is to provide a chronology of key events and events from 1989 to 2002 that led to the establishment of EMMARM, as well as some of the principles behind its establishment. Expand


Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement.
An aqueous decoction of mango stem bark extract is concluded that the product could be useful to prevent the production of reactive oxygen species and oxidative tissue damage in vivo. Expand
Breast Cancer. diagnosis (May 28 th
  • 2013
Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation
The anticancer activities of Pg extract in breast cancer cells were due in part to targeting microRNAs155 and 27a, which play an important role in the proliferative/inflammatory phenotype exhibited by these cell lines. Expand
Minireview: Inflammation: an instigator of more aggressive estrogen receptor (ER) positive breast cancers.
It is proposed that inflammation may promote more aggressive ER-positive tumors and that combination therapy targeting both inflammation and estrogen production or actions could benefit a significant portion of women whose ER- positive breast tumors fail to respond to endocrine therapy. Expand
Anticarcinogenic effects of polyphenolics from mango (Mangifera indica) varieties.
Overall, polyphenolics from several mango varieties exerted anticancer effects, where compounds from Haden and Ataulfo mango varieties possessed superior chemopreventive activity. Expand
Chemistry and Biochemistry of Dietary Polyphenols
  • R. Tsao
  • Biology, Medicine
  • Nutrients
  • 2010
The chemistry and biochemistry of polyphenols as related to classification, extraction, separation and analytical methods, their occurrence and biosynthesis in plants, and the biological activities and implications in human health are reviewed. Expand
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
The therapeutic potential of drugs targeting PI3K–Akt signalling for the treatment of cancer is discussed and the advantages and drawbacks of different treatment strategies for targeting this pathway are focused on. Expand
Major Mango Polyphenols and Their Potential Significance to Human Health.
  • M. Masibo, Q. He
  • Medicine, Chemistry
  • Comprehensive reviews in food science and food safety
  • 2008
The major mango polyphenols are reviewed, looking at their proposed antioxidative activity, estimated amounts in the different parts, their structures, suggested modes of action, and related significance to human health, with great emphasis on mangiferin. Expand
Modulatory Effects of Polyphenols on Apoptosis Induction: Relevance for Cancer Prevention
A deeper knowledge of the underlying mechanisms responsible for the modulation of apoptosis by polyphenols, and their real effectiveness, is necessary in order to propose them as potential chemopreventive and chemotherapeutic candidates for cancer treatment. Expand
Inflammation and cancer: how hot is the link?
The critical link between inflammation and cancer is described and observations imply that anti-inflammatory agents that suppress NF-kappaB or NF- kappaB-regulated products should have a potential in both the prevention and treatment of cancer. Expand