Anti-inflammatory and Analgesic Effects of the Methanol Stem Bark Extract of Brachystegia eurycoma Harms (Fabaceae)

@article{Igbe2012AntiinflammatoryAA,
  title={Anti-inflammatory and Analgesic Effects of the Methanol Stem Bark Extract of Brachystegia eurycoma Harms (Fabaceae)},
  author={I. Igbe and B. A. Ayinde and Abuajah Christian Izuchukwu},
  journal={European journal of medicinal plants},
  year={2012},
  volume={2},
  pages={356-365}
}
Aims: The aim of the study was to investigate the analgesic and anti-inflammatory activities of the methanol stem bark extract of Brachystegia eurycoma Harms. Place and Duration of Study: Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin. Methodology: Analgesic activity was examined using the hot plate and acetic acidinduced writhing test while acute anti-inflammatory effect was studied using carrageenan and dextran-induced paw edema. Results: Oral… 

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References

SHOWING 1-10 OF 47 REFERENCES
Antioxidant and antiinflammatory activities of the flowers of Tabernaemontana coronaria (l) R.BR
The ethanol and aqueous extracts of Tabernaemontana coronaria flowers possessed significant in vitro superoxide, hydroxyl radicals, nitric oxide scavenging, and lipid peroxidation inhibiting
Antipyretic and analgesic effects of the aqueous extract of the fruit pulp of Hunteria umbellata K Schum (Apocynaceae).
TLDR
The aqueous fruit pulp extract of Hunteria umbellata K. Schum possesses antipyretic and analgesic activities which validate its use in the treatment of pains and fevers.
Anti-inflammatory activity of aqueous fruit pulp extract of Hunteria umbellata K. Schum in acute and chronic inflammation.
TLDR
The results indicate that the aqueous extract of H. umbellata possesses acute inflammatory activity which may be mediated by either inhibition or by blocking the release of prostaglandins and histamine, thus supporting the usage of the plant in traditional medicine treatment of inflammation.
Growth inhibitory and cytotoxic effects of the methanol extract of Brachystegia eurycoma Harms (Fabaceae) leaves.
TLDR
The results obtained confirmed the probable use of B. eurycoma leaves in treating tumour related ailments and the activities are enhanced with partial purification with the aqueous fraction showing higher activities.
Analgesic and Antiinflammatory Effects of Two Chemotypes of Lippia alba: a Comparative Study
The antinociceptive and antiedematogenic effects of essential oils (EO, types I and II) from the leaves of two chemotypes of Lippia alba were studied with mice using the hot plate test, acetic
Phytochemical components of Hunteria umbellata (K. Schum) and its effect on isolated non-pregnant rat uterus in oestrus.
TLDR
It is revealed that Hunteria umbellata has oxytocic effect thus justifying the use by the traditional birth attendants and validating scientifically the ethno - medicinal usage.
Preliminary studies on antiinflammatory and analgesic activities of Spilanthes acmella in experimental animal models
TLDR
SPA showed dose-dependent action in all the experimental models and indicates that SPA has significant antiinflammatory and analgesic properties.
Effect of Cleome arabica Leaf Extract on Rat Paw Edema and Human Neutrophil Migration
TLDR
It appears that the antiinflammatory activity of Cleome arabica leaf extract, observed in vivo as well as in vitro, could be due to its high flavonoid content (19%).
Hypoglycaemic effects of the aqueous seed extract of Hunteria umbellata in normoglycaemic and glucose-and nicotine-induced hyperglycaemic rats
TLDR
The data generated in the present study has a strong positive correlation with its folkloric use in the treatment of suspected type 2 diabetic patients, although its use should be with great caution.
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