Anti-inflammatory activity of hydroxycinnamic acid derivatives isolated from corn bran in lipopolysaccharide-stimulated Raw 264.7 macrophages.

@article{Kim2012AntiinflammatoryAO,
  title={Anti-inflammatory activity of hydroxycinnamic acid derivatives isolated from corn bran in lipopolysaccharide-stimulated Raw 264.7 macrophages.},
  author={Eun Ok Kim and Kyoung Jin Min and Taeg Kyu Kwon and Byung Hun Um and Robert A. Moreau and Sang Won Choi},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2012},
  volume={50 5},
  pages={1309-16}
}
In this study, the effect of the 80% ethanolic extract of corn bran (EECB) on inhibition of nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated Raw 264.7 cells was investigated. The EECB inhibited LPS-induced NO production and iNOS expression in a dose-dependent manner. Four hydroxycinnamic acid derivatives (HADs), including two free cinnamic acids, p-coumaric acid (CA) and ferulic acid (FA), and their conjugate phenolic… CONTINUE READING