Anti-inflammatory activity of ethanolic extract of Sargassum sagamianum in RAW 264.7 cells

@article{Kim2013AntiinflammatoryAO,
  title={Anti-inflammatory activity of ethanolic extract of Sargassum sagamianum in RAW 264.7 cells},
  author={Min-Ji Kim and Koth-Bong-Woo-Ri Kim and Da-Hyun Jeong and Dong Hyun Ahn},
  journal={Food Science and Biotechnology},
  year={2013},
  volume={22},
  pages={1113-1120}
}
Aim of the study is to evaluate the antiinflammatory effects of ethanolic extract of the marine brown alga Sargassum sagamianum collected from Yeonhwari coast of Korea. Ethanolic extract of S. sagamianum (SA-E extract) inhibited expression of nitric oxide (NO) and cytokines (IL-6, IL-1β, and TNF-α) as well as inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 in lipopolysaccharide (LPS)-induced RAW 264.7 cells without affecting cell viability. In addition, the expression of… 
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Highly Influential Citations
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Methods Citations
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16 Citations

In vitro antiviral, anti-inflammatory, and antioxidant activities of the ethanol extract of Mentha piperita L.
TLDR
Results indicate that Mentha piperitas L. piperita L. leaves might be a good source of medicinal plants and show potential free-radical scavenging activities.
Enhanced anti-inflammatory activity of brown seaweed Laminaria japonica by fermentation using Bacillus subtilis
Sargassum sagamianum Extract Alleviates Postprandial Hyperglycemia in Diabetic Mice
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Results indicate that SSE can be used as an α-glucosidase and α-amylase inhibitor and can delay the absorption of dietary carbohydrates.
Inula britannica fermented with probiotic Weissella cibaria D30 exhibited anti-inflammatory effect and increased viability in RAW 264.7 cells
TLDR
Results indicate that FIB is a potential beneficial bioactive agent for functional foods and reduces the toxicity and increased the anti-inflammatory properties of I. britannica.
Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-κB Signaling Pathway
TLDR
Some of the mechanistic aspects behind the anti- inflammation capacity of phlorotannins from F. vesiculosus are unveiled, endorsing its use as a possible natural source of anti-inflammatory compounds.
Antioxidative, Anticholinesterase and Anti-Neuroinflammatory Properties of Malaysian Brown and Green Seaweeds
TLDR
An overview of the properties of Malaysian seaweeds in inhibiting oxidative stress, neuroinflammation and cholinesterase enzymes is provided and marine algae have great potential in pharmaceutical and biomedical applications.
Sargassum sagamianum extract protects INS-1 pancreatic β cells against high glucose-induced apoptosis
TLDR
It is suggested that SSE could be useful as a functional food, protecting pancreatic β cells against high glucose-induced oxidative stress and apoptosis, by recovering the cell viability.
Sargassum Seaweed as a Source of Anti-Inflammatory Substances and the Potential Insight of the Tropical Species: A Review
TLDR
This review aims to explore the potential of Sargassum’s anti-inflammatory activity, not only in crude extracts but also in sulfated polysaccharides and purified compounds.
In vitro bioactive properties of phlorotannins recovered from hydrothermal treatment of Sargassum muticum
Brown Algae Phlorotannins: A Marine Alternative to Break the Oxidative Stress, Inflammation and Cancer Network
TLDR
The present manuscript revises relevant studies focusing the effects of phlorotannins to counteract the oxidative stress–inflammation network, emphasizing their potential for application in cancer prevention and/or treatment.
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