Anti-inflammatory activity and percutaneous absorption of quercetin and its polymethoxylated compound and glycosides: the relationships to chemical structures.

The potential of quercetin-related compounds for topical application has not previously been systematically investigated. To better elucidate relationships of the structure and activity with skin permeation, some quercetin compounds were used as permeants, including aglycone, a polymethoxylated compound (quercetin 3,5,7,3',4'-pentamethylether, QM), and… CONTINUE READING