Anti-inflammatory activities of triterpenoid saponins from Polygala japonica.

  title={Anti-inflammatory activities of triterpenoid saponins from Polygala japonica.},
  author={Honglan Wang and Jianqing Gao and Jinghong Kou and D Zhu and Bing-ying Yu},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={15 5},
Bioassay-guided investigation was performed to identify the active constituents from a methanol extract of Polygala japonica, a folk medicinal plant widely used in China to treat inflammatory diseases. The n-BuOH and EtOAc fractions of the P. japonica methanol extract, which show significant anti-inflammatory activity in in vivo test, were further subjected to column chromatography to afford six triterpene glycosides, marked here as saponins 1-6. All compounds were evaluated for their anti… CONTINUE READING


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