Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance

@article{Engelhardt1995AntiinflammatoryAA,
  title={Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance},
  author={Guenther Dr Engelhardt and Daisuke Homma and Kristina Schlegel and Rene Utzmann and C. Schnitzler},
  journal={Inflammation Research},
  year={1995},
  volume={44},
  pages={423-433}
}
The anti-inflammatory, analgesic and antipyretic properties of the new non-steroidal anti-inflammatory agent, meloxicam, were investigated in a variety of animal models and compared with the properties of piroxicam, diclofenac, indomethacin and several other NSAIDs.With respect to the total effect of a single oral dose, the anti-exudative effect of meloxicam on carrageenaninduced oedema in the rat exceeded that of all the NSAIDs included in the comparison. Additionally, meloxicam showed the… 
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237 Citations
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237 Citations

Modulation of the pharmacological properties of meloxicam by octreotide in rats

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The safety index of preferential COX-2 inhibitor (nimesulide, meloxicam) was investigated using carrageenan-induced paw oedema and acute ulcerogenic model in rats, compared with the classical NSAIDs (naproxen, indomethacin).

A comparison between the effects of meloxicam and other nsaids on the production of oxyradicals by human polymorphonuclear leucocytes

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Role of Indomethacin in Acute Pain and Inflammation Management: A Review of the Literature

This review provides an historic overview of indomethacin and its efficacy compared with other commonly used analgesics, and discusses new indometHacin drug products.

Analgesic, Anti-Inflammatory and Ulcerogenic Studies of Meloxicam Solid Dispersion in Rodents

Results indicate that both physical mixture and solid dispersion possess better analgesic and anti-inflammatory properties with less ulcerogenic potential as compared to pure meloxicam.

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Results indicate that solid dispersion possess better analgesic and anti-inflammatory properties with less ulcerogenic potential as compared to pure meloxicam.

Interaction of meloxicam and phenylbutazone on the level of cyclooxygenase-2 in mice

The reason for the recent study was to inspect the therapeutic efficacy of meloxicam and phenylbutazone alone with their analgesic interaction and their subsequent inhibitory interaction at the level…

Meloxicam: A potent inhibitor of adjuvant arthritis in the Lewis rat

Findings indicate that the action of meloxicam and piroxicam differs from that of diclofenac and tenidap in adjuvant arthritis in the Lewis rat.
...

References

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