Anti-immunoglobulin and Phorbol Ester Induce Phosphorylation f Proteins Associated with the Plasma Membrane and Cytoskeleton in Murine

Protein phosphorylations are rapidly induced in intact B cells by antibodies to surface immunoglobulin (anti-IgM) and by phorbol 12-myristate 13-acetate (PMA). A comparison of the molecular weight, isoelectric points, phosphopeptides, and phosphoamino acids of the phosphoproteins induced by anti-IgM and by PMA suggests that anti-IgM acts through the… CONTINUE READING