Anti-immunoglobulin E therapy for asthma.

  title={Anti-immunoglobulin E therapy for asthma.},
  author={Charles E. Owen},
  journal={Pulmonary pharmacology & therapeutics},
  volume={15 5},
The role of immunoglobulin E (IgE) in allergic asthmatic disease is well established. Allergen-specific IgE binds to its cognate receptors, thus triggering a series of cellular events. These events include presentation of antigen by dendritic cells and the degranulation of mast cells and basophils to release numerous factors that play an integral part in… CONTINUE READING