Anti-idiotypic immunity and autoimmunity: III. Investigations in human autoimmune thyroiditis.


We have recently shown that autoantibodies to thyroglobulin in from rats with spontaneous autoimmune thyroiditis share idiotypic determinants and can be characterized using heterologous anti-idiotypic antibodies. We have also shown that cross-reacting idiotypic determinants are present on autoantibodies to rat thyroglobulin from rats with experimentally… (More)


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