Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditis.

@article{Caforio2010AntiheartAA,
  title={Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditis.},
  author={Alida Linda Caforio and Antonio L Brucato and Andrea Doria and Gabriella Brambilla and Alessia Angelini and Anna Ghirardello and Stefania Bottaro and Federico Tona and Corrado Betterle and Luciano Daliento and Gaetano Thiene and Sabino Iliceto},
  journal={Heart},
  year={2010},
  volume={96 10},
  pages={779-84}
}
BACKGROUND Idiopathic recurrent acute pericarditis (IRAP) is a rare disease of suspected, yet unproved, immune-mediated origin. The finding of serum heart-specific autoantibodies in IRAP would strengthen the autoimmune hypothesis and provide aetiology-specific non-invasive biomarkers. Objective To assess frequency of serum anti-heart (AHA), anti-intercalated-disk (AIDA) and non-cardiac-specific autoantibodies and their clinical and instrumental correlates in patients with IRAP. Patients 40… CONTINUE READING