Anti-granuloma activity of Iraqi Withania somnifera.

  title={Anti-granuloma activity of Iraqi Withania somnifera.},
  author={M K al-Hindawi and S H al-Khafaji and M H Abdul-Nabi},
  journal={Journal of ethnopharmacology},
  volume={37 2},
The granuloma-tissue formation inhibiting activity of various fractions of an extract of the aerial parts of Withania somnifera were established using subcutaneous cotton-pellet implantation in rats. Antiinflammatory activity was retained in the methanolic fractions of the plant extract and was comparable to that of a 5 mg/kg dose of hydrocortisone sodium succinate. Activity was attributed to the high content of biologically active steroids in the plant, of which withaferin A is known to be a… CONTINUE READING
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