Anti-fibrotic effects of Salvia miltiorrhiza and Ligustrazine Injection on LX-2 cells involved with increased N-myc downstream-regulated gene 2 expression.

@article{Zheng2017AntifibroticEO,
  title={Anti-fibrotic effects of Salvia miltiorrhiza and Ligustrazine Injection on LX-2 cells involved with increased N-myc downstream-regulated gene 2 expression.},
  author={Jin E. Zheng and Li-tian Ma and Qin-you Ren and Yue Qing Hu and Yang Bai and Huan Bian and Yi Zhang and Yongchun Zhou and Minghui Yang},
  journal={Chinese journal of integrative medicine},
  year={2017},
  volume={23 12},
  pages={
          923-928
        }
}
OBJECTIVE To investigate the effects of Salvia miltiorrhiza and Ligustrazine Injection (SML) on proliferation and apoptosis of human hepatic stellate cell LX-2 and the expression of N-myc downstreamregulated gene 2 (NDRG2, a tumor suppressor gene). METHODS HSCs from the LX-2 cell line were cultured in vitro. The proliferative state of different initial LX… CONTINUE READING