Anti-epileptic medication and bone health

  title={Anti-epileptic medication and bone health},
  author={S. Petty and T. O'Brien and J. D. Wark},
  journal={Osteoporosis International},
  • S. Petty, T. O'Brien, J. D. Wark
  • Published 2006
  • Medicine
  • Osteoporosis International
  • BackgroundEpilepsy is a common chronic neurological disorder, usually requiring long-term treatment with anti-epileptic drugs (AED). Many studies have reported that AED therapy is associated with metabolic bone disease and is a major iatrogenic risk factor for fractures. There remains uncertainty about the type(s) of bone disease due to AED treatment, and the pathogenesis of AED-associated fractures.RationaleDeficits in bone mineral density (BMD) are widely reported in AED-treated patient… CONTINUE READING
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