Anti-epileptic medication and bone health

  title={Anti-epileptic medication and bone health},
  author={Sandra J. Petty and Timothy J. O’Brien and J. D. Wark},
  journal={Osteoporosis International},
Epilepsy is a common chronic neurological disorder, usually requiring long-term treatment with anti-epileptic drugs (AED). Many studies have reported that AED therapy is associated with metabolic bone disease and is a major iatrogenic risk factor for fractures. There remains uncertainty about the type(s) of bone disease due to AED treatment, and the pathogenesis of AED-associated fractures. Deficits in bone mineral density (BMD) are widely reported in AED-treated patient populations. However… CONTINUE READING


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