Anti-endothelial cell antibodies (AECA) in patients with systemic vasculitis: our research using proteomics.

@article{Karasawa2011AntiendothelialCA,
  title={Anti-endothelial cell antibodies (AECA) in patients with systemic vasculitis: our research using proteomics.},
  author={Rie Karasawa and Kazuo Yudoh and Shoichi Ozaki and Tomohiro Kato},
  journal={Expert opinion on biological therapy},
  year={2011},
  volume={11 1},
  pages={77-87}
}
IMPORTANCE OF THE FIELD Anti-endothelial cell antibodies (AECA) may cause damage to endothelial cell (EC) functions and therefore may be of a pathophysiological role in systemic vasculitis. The pathophysiological role of AECA, however, is still uncertain. AREAS COVERED IN THIS REVIEW To clarify the detailed roles of AECA, various methods for identification of target proteins of AECA have been developed, such as expression libraries and proteomic approaches combining two-dimensional… CONTINUE READING

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