Anti-dsDNA antibody avidity determination by a simple reliable ELISA method for SLE diagnosis and monitoring.

Abstract

High avidity anti-dsDNA antibodies are more specific for SLE diagnosis, and more closely associated with renal involvement than intermediate or low-affinity anti-dsDNA antibodies. ELISA methods are largely used to detect anti-dsDNA, but their high sensitivity is inversely related to specificity because they also detect low avidity antibodies. We developed… (More)

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Cite this paper

@article{Villalta2003AntidsDNAAA, title={Anti-dsDNA antibody avidity determination by a simple reliable ELISA method for SLE diagnosis and monitoring.}, author={Dino L Villalta and P B Romelli and C. Savina and Nicola Bizzaro and Renato Tozzoli and Emil Tonutti and Amanda Ghirardello and Alessandro Doria}, journal={Lupus}, year={2003}, volume={12 1}, pages={31-6} }