Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice.

  title={Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice.},
  author={Su-Nam Kim and Woojung Lee and Gyu-Un Bae and Yong Kee Kim},
  journal={Biochemical and biophysical research communications},
  volume={424 4},
Peroxisome proliferator-activated receptors (PPARs) have been considered to be desirable targets for metabolic syndrome, even though their specific agonists have several side effects including body weight gain, edema and tissue failure. Previously, we have reported in vitro effects of Sargassum yezoense (SY) and its ingredients, sargaquinoic acid (SQA) and sargahydroquinoic acid (SHQA), on PPARα/γ dual transcriptional activation. In this study, we describe in vivo pharmacological property of SY… CONTINUE READING


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