Anti-diabetic activity of β-glucans and their enzymatically hydrolyzed oligosaccharides from Agaricus blazei

@article{Kim2005AntidiabeticAO,
  title={Anti-diabetic activity of β-glucans and their enzymatically hydrolyzed oligosaccharides from Agaricus blazei},
  author={Y. Kim and Ki-Hoon Kim and Hyun-Ju Choi and Dong-Seok Lee},
  journal={Biotechnology Letters},
  year={2005},
  volume={27},
  pages={483-487}
}
β-Glucans were prepared from Agaricus blazei Murill by repeated extraction with hot water. The average molecular weights of β-glucans were 30–50 kDa by gel filtration chromatography. Oligosaccharides (AO), derived from hydrolyzing β-glucans with an endo-β-(1→6)-glucanase from Bacillus megaterium, were mainly di- and tri-saccharides. Though β-glucans and AO both showed anti-hyperglycemic, anti-hypertriglyceridemic, anti-hypercholesterolemic, and anti-arteriosclerotic activity indicating overall… CONTINUE READING

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