Anti-diabetic activities of the methanol leaf extracts of Hymenocardia acida (tul.) in alloxan-induced diabetic rats.

@article{Ezeigbo2012AntidiabeticAO,
  title={Anti-diabetic activities of the methanol leaf extracts of Hymenocardia acida (tul.) in alloxan-induced diabetic rats.},
  author={Ihechiluru I. Ezeigbo and Isaac Uzoma Asuzu},
  journal={African journal of traditional, complementary, and alternative medicines : AJTCAM},
  year={2012},
  volume={9 2},
  pages={
          204-9
        }
}
  • I. Ezeigbo, I. U. Asuzu
  • Published 2012
  • Biology, Medicine, Chemistry
  • African journal of traditional, complementary, and alternative medicines : AJTCAM
The effect of methanolic extract of Hymenocardia acida leaves on diabetes and associated lipidemia were investigated on experimentally-induced diabetic rats. The extract did not demonstrate any acutely toxic effect in rats within the dose range (250 mg/kg - 2000 mg/kg) employed in the study; hence it was well tolerated by the rats. In all experiments, the anti-diabetic effects were dose-dependent and comparable to that of glibenclamide (2 mg/kg) standard. At a dose of 500 mg/kg, lipid profile… 
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