Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells.

@article{Lee2014AntidiabeticAO,
  title={Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells.},
  author={Young-Sun Lee and Hee-Sook Jun},
  journal={Metabolism: clinical and experimental},
  year={2014},
  volume={63 1},
  pages={9-19}
}
Glucagon-like peptide-1 (GLP-1), an incretin hormone, is released from intestinal L-cells in response to nutrients. GLP-1 lowers blood glucose levels by stimulating insulin secretion from pancreatic beta-cells in a glucose-dependent manner. In addition, GLP-1 slows gastric emptying, suppresses appetite, reduces plasma glucagon, and stimulates glucose disposal, which are beneficial for glucose homeostasis. Therefore, incretin-based therapies such as GLP-1 receptor agonists and inhibitors of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
43 Citations
103 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 103 references

The role of incretins in glucose homeostasis and diabetes treatment

  • KimW, JM Egan
  • Pharmacol Rev 2008;60:470–512
  • 2008
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…