Anti-dermatitis effects of oak wood vinegar on the DNCB-induced contact hypersensitivity via STAT3 suppression.

  title={Anti-dermatitis effects of oak wood vinegar on the DNCB-induced contact hypersensitivity via STAT3 suppression.},
  author={C S Lee and Eun Hee Yi and Hang-Rae Kim and Sang-Rok Huh and Sang Hyun Sung and M R Chung and Sang-Kyu Ye},
  journal={Journal of ethnopharmacology},
  volume={135 3},
AIMS OF THE STUDY The aim of this study was to evaluate the anti-dermatitis effects of oak wood vinegar (OWV) in a 2,4-dinitrochlorobenzene (DNCB)-induced contact dermatitis mice model. MATERIALS AND METHODS Immunoglobulin E (IgE) production, infiltration of immune cells (neutrophils, CD3+ cells), inducible nitric oxide synthase (iNOS) expression, skin thickness, and expression of phosphorylated STAT3 (signal transducers and activators of transcription 3) protein were tested in a DNCB-induced… CONTINUE READING
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