Anti-cardiolipin antibodies in neurological disorders: cross-reaction with anti-single stranded DNA activity.

@article{Colao1987AnticardiolipinAI,
  title={Anti-cardiolipin antibodies in neurological disorders: cross-reaction with anti-single stranded DNA activity.},
  author={C Bernie Colaço and Glenis Kathleen Scadding and Stephen Lockhart},
  journal={Clinical and experimental immunology},
  year={1987},
  volume={68 2},
  pages={313-9}
}
Antiphospholipid (PL) antibodies have been detected in sera from patients with chronic neurological diseases associated with disorders of immunity. In an isotype specific radioimmunoassay for anti-cardiolipin (CL) antibodies, we found IgM anti-CL (greater than 2 s.d. above mean of controls) in 17/25 (68%) patients with myasthenia gravis (MG), 8/25 (32%) with the Lambert-Eaton myasthenic syndrome (LEMS), 5/17 (29%) with multiple sclerosis and 3/11 (27%) cases of migraine. IgG anti-CL was only… CONTINUE READING

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