Anti-cancer drug development: computational strategies to identify and target proteins involved in cancer metabolism.

Abstract

Cancer remains a fundamental burden to public health despite substantial efforts aimed at developing effective chemotherapeutics and significant advances in chemotherapeutic regimens. The major challenge in anti-cancer drug design is to selectively target cancer cells with high specificity. Research into treating malignancies by targeting altered metabolism… (More)

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@article{Mak2013AnticancerDD, title={Anti-cancer drug development: computational strategies to identify and target proteins involved in cancer metabolism.}, author={Lora Mak and Sonia Liggi and Lu Tan and Kanthida Kusonmano and Judith M. Rollinger and Alexios Koutsoukas and Robert C. Glen and Johannes Kirchmair}, journal={Current pharmaceutical design}, year={2013}, volume={19 4}, pages={532-77} }