Anti-cancer activity of compounds from Bauhinia strychnifolia stem.

  title={Anti-cancer activity of compounds from Bauhinia strychnifolia stem.},
  author={S. Yuenyongsawad and K. Bunluepuech and C. Wattanapiromsakul and S. Tewtrakul},
  journal={Journal of ethnopharmacology},
  volume={150 2},
ETHNOPHARMACOLOGICAL RELEVANCE The stem and root of Bauhinia strychnifolia Craib (Fabaceae family) have been traditionally used in Thailand to treat fever, alcoholic toxication, allergy and cancer. An EtOH extract of Bauhinia strychnifolia showed good inhibitory activity against several cancer cell lines including HT-29, HeLa, MCF-7 and KB. As there has been no previous reports on chemical constituents of Bauhinia strychnifolia, this study is aimed to isolate the pure compounds with anti-cancer… Expand
Antimalarial Activity of Ethanolic Leaf Extract of Bauhinia strychnifolia inMice Infected with Plasmodium berghei
Results indicate that ethanolic crude extract of B. strychnifolia leaves has excellent in vivo antimalarial activities against P. berghei ANKA, Hence, this plant extract represents a promising source of new antimalaria agents. Expand
Yanangdaengin, a dihydrochalcone glucoside galloyl ester as active antioxidative agent from leaves of Lysiphyllum strychnifolium (syn. Bauhinia strychnifolia)
Abstract Objective To isolate and identify the major bioactive components from the leaves of Lysiphyllum strychnifolium, an indigenous herb used in traditional Thai medicine for detoxification,Expand
Chemical composition, larvicidal and cytotoxic activities of the leaf essential oil of Bauhinia cheilantha (Bong.) Steud
Abstract The essential oil obtained by hydrodistillation from fresh leaves of Bauhinia cheilantha was analysed by GC-FID and GC-MS. The chemical composition of the essential oil was dominated byExpand
Anti-HIV-1 Protease Activity of Compounds from Cassia garrettiana
For the purpose of discovering anti-HIV-1 agents from Thai plant preparations with a history of use in Thai traditional medicine as agents assisting health longevity, aqueous and ethanol extractsExpand
In Vitro Antioxidant Activities of Extracts of Bauhinia strychnifolia Stems and Leaves: Comparison with Activities in Green Tea Extracts
Dried stems and leaves of Yha-nang dang (Bauhinia strychnifolia Craib.) have long been used in Thailand to make tea for promoting health and for detoxification of the body. The objectives of thisExpand
New Cytotoxic Bibenzyl and Other Constituents from Bauhinia ungulata L. (Fabaceae)
The cytotoxicity of the bibenzyl 1 has been evaluated against four human cancer cell lines, showing the IC50 values of 4.3 and 6.5 μg ml−1 against pro‐myelocytic leukemia (HL‐60) and cervical adenocarcinoma (HEP‐2) cell Lines, respectively. Expand
Effect of Crude Leaf Extract of Bauhinia strychnifolia in BALB/c Mice Infectedwith Plasmodium berghei
It is suggested that the crude leaf extract of this plant have promising antimalarial activity against P. berghei in a dose dependent manner, which supports the folkloric use of the plant for treating malaria. Expand
Antioxidant Activity of Fourteen Herbal Plants In Thailand
Herbal plants are responsible as the good sources of bioactive substances, which are potential to be further alternative remedies for mankind and animals. This work studies the antioxidant activityExpand
Cancer has been the most dreadful disease from ages till now. However, with the passage of time it been more understood its mechanism, types, some causing factors, and way of its cell duplication. ByExpand
Screening of plant collection of Cibodas Botanic Gardens, Indonesia with anticancer properties
Inventory and categorize plant collections in Cibodas Botanic Gardens (CBG), West Java, Indonesia that has anticancer properties in a detailed and comprehensive manner and can serve as baseline information for further research in drug discovery and development for anticancer treatments using living plant specimens collected in CBG. Expand


Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells.
It is demonstrated that genistein (6) induces apoptosis in SK-Hep-1 cells via both Fas- and mitochondria-mediated pathways. Expand
Anti-tyrosinase and anti-cancer activities of flavonoids from Blumea balsamifera DC
Fractionation of an ethylacetate extract from leaves of Blumea balsamifera DC, led to isolation of nine flavonoids. The isolated compounds consisted of two dihydroflavonols,Expand
Anticancer activity of guava ( Psidium guajava L.) branch extracts against HT-29 human colon cancer cells
During the course of screening, it was found that the acetone extracts of guava (Psidium guajava L.) branch (GBA) had cytotoxic effects on HT-29 cells, and GBA induced characteristic apoptotic effects in HT- 29 cells, including chromatin condensation and sharking. Expand
Evaluation of the anti-inflammatory, antinociceptive and antipyretic activities of the extracts from Smilax corbularia Kunth rhizomes in mice and rats (in vivo)
Results suggest that the ethanol extract of S. corbularia rhizomes possess anti-inflammatory activity, and that its actions on the inflammation may be different from those of aspirin. Expand
Evaluation of the Antineoplastic Activity of L-rhamnose in vitro. A Comparison with 2-deoxyglucose.
From the lacking inhibition of the protein synthesis it can be considered that L-rhamnose does not interfere with energy metabolism, at least not in a similar manner as 2-DG. Expand
Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells.
  • S. Kuo
  • Biology, Medicine
  • Cancer letters
  • 1996
Of the two most potent flavonoids, quercetin and genistein, the effect was found to be dose-dependent and chromatin condensation, an indication of apoptosis, was noticed and the chemical instability did not correlate with the antiproliferative potency, although it may contribute to the antiprologative effect. Expand
Cytotoxic Isoquinoline Quinones from the Thai Sponge Cribrochalina
It was found that all three isoquinoline quinones were highly active, especially against MCF-7 breast carcinoma and HeLa cervical cancer cell lines, and this report is the first isolation of (+)-enantiomer of N -formyl-1,2-dihydrorenierone from a naturally occurring source. Expand
Flavonol Glycosides from Asperula arvensis L.
From the aerial parts of Asperula arvensis L. 9 known flavonol glycosides, namely quercetin (1), isoquercitrin [= quercetin 3-O-b-glucopyranoside] (2), hyperin [= quercetin 3-O-b -galactopyranoside]Expand
Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase‐3‐dependent apoptosis in oral cavity cancer cells
It is suggested that kaempferol and quercetin, two components of EGb 761, effectively induce caspase‐3‐dependent apoptosis of oral cavity cancer cells and can be considered as possible anti‐oral cavity cancer agents. Expand
Quercetin and Cancer Chemoprevention
The molecular mechanisms that are based on the biological effects of Qu, and their relevance for human health are discussed, including the high toxicity exerted by Qu on cancer cells perfectly matches with the almost total absence of any damages for normal, non-transformed cells. Expand