• Corpus ID: 39085626

Anti bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus.

@article{Hannan2008AntiBA,
  title={Anti bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus.},
  author={A. . Irrigation Hannan and Sidrah Saleem and Saadia Chaudhary and Muhammad Barkaat Hussain and Muhammad Usman Arshad},
  journal={Journal of Ayub Medical College, Abbottabad : JAMC},
  year={2008},
  volume={20 3},
  pages={
          72-4
        }
}
BACKGROUND Methicillin resistant Staphylococcus aureus (MRSA) continues to be one of the commonest pathogens encountered in clinical as well as laboratory practice. It has become a major health problem worldwide. Newer antimicrobials/agents are urgently needed to combat this problem MRSA resistance to various anti-staphylococcal agents. In the back-drop of this difficult situation Nigella sativa commonly known as black seed (ethanolic extract) was aimed at to evaluate if it had any anti… 

Tables from this paper

Assessment of In vitro Antibacterial Activity and Cytotoxicity Effect of Nigella sativa Oil
TLDR
There is a requirement for further clinical trials on N. sativa oil for "safe" medical management of infections caused by methicillin-resistant Staphylococci, as the oil was very active against MRSA and MRCoNS and had no in vitro cytotoxicity at relevant concentrations.
In vitro profiling of antimethicillin‐resistant Staphylococcus aureus activity of thymoquinone against selected type and clinical strains
TLDR
In conclusion, MIC90, bactericidal property, longer PAE, absence of resistant mutant selection and damages in cell membrane and cell wall imply a promising anti‐MRSA activity of thymoquinone.
Antibacterial activity of Nigella sativa seed in various germination phases on clinical bacterial strains isolated from human patients
TLDR
The distilled methanolic extracts of N. sativa showed significant antimicrobial activity against tested clinical strains of Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis bacteria.
Antimicrobial activity of PVP from an Antarctic bacterium, Janthinobacterium sp. Ant5-2, on multi-drug and methicillin resistant Staphylococcus aureus
TLDR
In silico predictive molecular docking study revealed that PVP could be a DNA-targeting minor groove binding antimicrobial compound that could stem the rising pandemic of MDR and MRSA along with other deadly microbial pathogens.
Finding Novel Antibiotic Substances from Medicinal Plants – Antimicrobial Properties of Nigella Sativa Directed against Multidrug-resistant Bacteria
TLDR
In vitro studies published between 2000 and 2015 revealed potent antimicrobial properties of N. sativa against MDR strains in vitro that should be further investigated in order to develop novel therapeutic perspectives for combating infectious diseases particularly caused by M DR strains.
Impact of Antibacterial Activity of Physical Storage Extracts on Pathogenic Bacteria
The overuse of antibiotics can lead to resistance among pathogenic bacteria. A new antibiotic that is effective against new and resistant bacterial strains is needed. Plants and marine organisms
Antibacterial Effect of Seed Extracts of Cardamom (Elettaria cardamomum) against Staphylococcus aureus and Proteus mirabilis
TLDR
It is cleared from this study that methanolic extract was better than ethanolic and aqueous extracts where the curing percentage was 3.33%-70%) and the results of plasmid curing was very weak where methanolics extract cured only 3.
In vitro study of antimicrobial activity of some plant seeds against bacterial strains causing food poisoning diseases.
TLDR
Plant seeds powder have promising antimicrobial activities and their potential applications in food process could be utilized as a natural medicinal alternative instead of chemical substance.
In vitro study of antimicrobial activity of some plant seeds against bacterial strains causing food poisoning diseases
In this research, some plant seeds powder was evaluated to find their potential effect to rule diseases of food poisoning. Antimicrobial effect of five plant seeds was examined contra Bacillus
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 14 REFERENCES
Antibacterial Activity of Certain Iranian Medicinal Plants Against Methicillin-Resistant and Sensitive Staphylococcus aureus
TLDR
Investigation of the antimicrobial activity of alcoholic and aqueous extract of 23 medical plants species of Golestan province on clinical and standard stains of MRSA and MSSA showed that ethanolic extract had better antibacterial effect than aQueous extract and anti staphylococcal activity of Ethanolic extract of plants against MRSA was better than MSSA strains.
Antibacterial and antifungal effects of Nigella sativa extracts against S. aureus, P. aeroginosa and C. albicans
TLDR
The antibacterial and antifungal effects of the aqueous, methanol and chloroform extracts of Nigella sativa seeds against standard and hospital strains of Candida albicans, coagulase-positive Staphylococcus aureus and Pseudomonas aeroginosa were investigated and compared with standard drugs.
Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus.
TLDR
Strains of Staphylococcus aureus with reduced susceptibility to glycopeptides have been reported from Japan, the United States, Europe, and the Far East, and there are increasing reports of strains showing heteroresistance.
Bactericidal activity of different honeys against pathogenic bacteria.
Methicillin resistant Staphylococcus aureus (MRSA) in the intensive care unit
TLDR
New antibiotics have been recently released that add to the armamentarium for therapy against MRSA and include linezolid, and quinupristin/dalfopristin, but cost, side effects, and resistance may limit their long term usefulness.
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
TLDR
This work analyzes an international collection of 912 MRSA and methicillin-susceptible S. aureus isolates to establish the likely evolutionary origins of each major MRSA clone, the genotype of the original MRSAclone and its MSSA progenitor, and the extent of acquisition and horizontal movement of the methiillin resistance genes.
Pharmacological and toxicological properties of Nigella sativa
TLDR
The main reports of the pharmacological and toxicological properties of N. sativa and its constituents are reviewed, which include asthma, diarrhoea and dyslipidaemia.
Antibacterial and antifungal effects of Nigella sativa extracts against S. aureus
  • P. aeroginosa and C. albicans. Pak J Med Sci
  • 2005
...
1
2
...